Kura Oncology reports encouraging long-term results for ziftomenib in AML
The Phase 1/2 KOMET-007 trial showed high remission rates and 94% 12-month OS in NPM1-m AML patients.
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Precision oncology therapeutics developer
kuraoncology.comLast updated
In short: Kura Oncology achieved FDA approval for KOMZIFTI and reported strong clinical data for its AML and solid tumor programs through early 2026.
The Phase 1/2 KOMET-007 trial showed high remission rates and 94% 12-month OS in NPM1-m AML patients.
Preliminary Phase 1a data show 67% ORR in pancreatic cancer, and a platform study is planned to start in early 2027.
The publication reports 87% ORR and 70% CRc in venetoclax-naïve patients with R/R NPM1-m AML.
Combination with adagrasib produced high response rates in PDAC, NSCLC and CRC, including KRASi-experienced patients, with manageable safety.
OS rate 94% among NPM1-m AML patients and 71% among KMT2A-r AML patients in single-arm KOMET-007 trial – – 96% CRc in newly ...
In a report released today, from Wedbush reiterated a Buy rating on Kura Oncology, with a price target of $36.00. Claim 55% Off TipRanks. Unlock...
Preliminary Phase 1a data from darlifarnib + adagrasib demonstrate confirmed, objective response rates of 67% in pancreatic cancer, 50% in non-small cell lung cancer, and...
ORR and 70% CRc in venetoclax-naïve and 48% ORR and 24% CRc in venetoclax-experienced patients at the recommended 600 mg once ...
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