Imugene reports positive azer-cel combination trial data
Cohort 3 showed 71% ORR. Combined ORR is 75%, demonstrating consistent efficacy across CAR-T and BTKi populations.
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Clinical-stage cell therapy company
imugene.comLast updated
In short: Imugene reported strong azer-cel trial responses, secured funding, and advanced its CAR-T pipeline with FDA fast-track status.
Cohort 3 showed 71% ORR. Combined ORR is 75%, demonstrating consistent efficacy across CAR-T and BTKi populations.
Both follicular lymphoma patients responded to azer-cel and BTKi therapy after prior relapse.
Both evaluable patients in the BTKi cohort responded, including the first Mantle Cell Lymphoma patient after BTKi resistance.
First patient in BTKi cohort achieved complete response at Day 28; four patients dosed and enrolment continues across 15 sites.
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