Blueprint Medicines announces four-year PIONEER data for AYVAKIT
Data show sustained symptom control, quality of life improvement, and long-term safety in indolent systemic mastocytosis patients. Presented at 2026 AAAAI Annual Meeting.
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Global biopharmaceutical company
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In short: Blueprint Medicines agreed to be acquired by Sanofi for $9.5 billion and regained global rights to Gavreto after Roche terminated their partnership.
Data show sustained symptom control, quality of life improvement, and long-term safety in indolent systemic mastocytosis patients. Presented at 2026 AAAAI Annual Meeting.
Data from PIONEER and PATHFINDER trials show sustained symptom control, quality-of-life improvements, prolonged survival, and bone health benefits in ISM and advanced SM.
Data from PIONEER, PATHFINDER, and EXPLORER trials reinforce sustained efficacy and safety in systemic mastocytosis treatment. Presentations include oral and flash talks.
The deal values Blueprint at $9.1 billion upfront, plus up to $0.6 billion in CVRs for BLU-808 milestones. It adds Ayvakit for systemic mastocytosis and immunology pipeline to Sanofi's portfolio.
These compelling results have ... and treatment durations trending toward multiple years,” Becker Hewes, MD, Chief Medical Officer at Blueprint Medicines, said in an earlier...
Blueprint Medicines Corporation will regain global commercialization and development rights to Gavreto (pralsetinib).
New four-year clinical data from Blueprint Medicines, a Sanofi company, show that Ayvakit (avapritinib) enabled sustained symptom control in patients with the rare disease indolent...
CAMBRIDGE, Mass., Feb. 28, 2026 /PRNewswire/ -- Blueprint Medicines, a Sanofi company, today announced AYVAKIT® (avapritinib) data showing clinically meaningful outcomes and a well-tolerated long-term...
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