Novartis reports del-desiran Phase III trial misses primary endpoint
The therapy shows activity in secondary analyses. Novartis will analyze full data and consult regulators while advancing other neuromuscular programs.
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Innovative medicines company
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In short: Novartis experienced significant stock declines following major late-stage trial failures, even as it secured several key drug approvals.
The therapy shows activity in secondary analyses. Novartis will analyze full data and consult regulators while advancing other neuromuscular programs.
The study achieved lower lipoprotein(a) levels but did not reduce cardiovascular events compared to placebo in over 8,000 patients with established disease.
The five-year initiative treated nearly three hundred children across forty nations before transitioning to commercial approvals in more than fifty countries.
The approval expands Pluvicto's use to PSMA-positive metastatic hormone-sensitive prostate cancer, nearly doubling eligible patients. Phase III PSMAddition showed 33% risk reduction in progression or death.
The pharmaceutical company Novartis has halted the development of the drug candidate VHB937 for the treatment of amyotrophic lateral sclerosis (ALS).
A Lutathera copycat has become the first “radioligand equivalent” cleared by regulators. Elsewhere, ...
The bad diagnoses just keep on coming for the Swiss drugmaker.
Novartis faces increased investor scrutiny over its mergers and acquisitions strategy following setbacks with acquired drugs.
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