Candel Therapeutics announces Lancet Oncology phase 3 publication
The publication reports a pivotal phase 3 trial showing 30% improvement in disease-free survival with aglatimagene plus radiotherapy and supports a planned BLA submission in Q4 2026.
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Clinical-stage biotech developing viral immunotherapy platforms for solid tumors
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In short: Candel Therapeutics reported pivotal phase 3 data for its prostate cancer therapy and finalized plans for a BLA submission in late 2026.
The publication reports a pivotal phase 3 trial showing 30% improvement in disease-free survival with aglatimagene plus radiotherapy and supports a planned BLA submission in Q4 2026.
Phase 3 trial of CAN-2409 shows 39% improvement in disease-free survival after prolonged follow-up, reinforcing potential to reduce tumor recurrence.
The company is developing CAN-2409 for prostate and lung cancer, and CAN-3110 for recurrent high-grade glioma.
Data shows 50% of NSCLC patients surviving beyond 24 months, supporting phase 3 trial initiation.
For patients with localized prostate cancer, aglatimagene besadenovec, an adenoviral-based immunotherapy, plus valacyclovir is associated with longer disease-free survival (DFS) than placebo plus valacyclovir when...
Peer reviewed publication details pivotal data, demonstrating 30% improvement in disease-free survival (DFS) in patients with localized prostate cancer undergoing standard-of-care radiotherapy with curative intent...
Candel Therapeutics (NASDAQ:CADL – Get Free Report) was downgraded by research analysts at Wall Street Zen from a “hold” rating to a “sell” rating in...
Chief Executive Officer Dr. Paul Peter Tak said the company remains focused on advancing its viral immunotherapy programs following newly presented prostate cancer data and...
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