Candel initiates Phase 3 AURORA trial for aglatimagene in NSCLC
The global phase 3 trial will evaluate aglatimagene plus valacyclovir and pembrolizumab versus docetaxel in metastatic NSCLC patients with prior progression.
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Clinical-stage biotech developing viral immunotherapy platforms for solid tumors
candeltx.comLast updated
In short: Candel Therapeutics advanced its oncology pipeline, highlighted by plans to submit a BLA for aglatimagene besadenovec in prostate cancer.
The global phase 3 trial will evaluate aglatimagene plus valacyclovir and pembrolizumab versus docetaxel in metastatic NSCLC patients with prior progression.
Sims will lead commercial strategy and launch readiness for aglatimagene besadenovec in localized prostate cancer.
The publication reports a pivotal phase 3 trial showing 30% improvement in disease-free survival with aglatimagene plus radiotherapy and supports a planned BLA submission in Q4 2026.
Phase 3 trial of CAN-2409 shows 39% improvement in disease-free survival after prolonged follow-up, reinforcing potential to reduce tumor recurrence.
CANDEL THERAPEUTICS, INC.
Shares of Candel Therapeutics rose after the company said it was initiating a pivotal Phase 3 trial to evaluate a lung-cancer treatment. Shares were up...
For patients with localized prostate cancer, aglatimagene besadenovec, an adenoviral-based immunotherapy, plus valacyclovir is associated with longer disease-free survival (DFS) than placebo plus valacyclovir when...
Peer reviewed publication details pivotal data, demonstrating 30% improvement in disease-free survival (DFS) in patients with localized prostate cancer undergoing standard-of-care radiotherapy with curative intent...
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