Annexon expands vonaprument Phase 3 program with Month 24 endpoint
Adds dual primary endpoint and launches open-label extension study for geographic atrophy treatment.
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Developer of C1q inhibitors for complement-driven diseases
annexonbio.comLast updated
In short: Annexon Biosciences filed for regulatory approval of tanruprubart for GBS and progressed its Phase 3 program for geographic atrophy.
Adds dual primary endpoint and launches open-label extension study for geographic atrophy treatment.
BLA submission for tanruprubart expected in Q4 2026; vonaprument Phase 3 on track; $200M credit facility extends runway into 2028.
All ten treated patients improved within one week, including four bedbound patients who walked by day eight; supports Q4 2026 BLA submission.
The non-dilutive funding supports progress toward registration for vonaprument and tanruprubart.
On Thursday, 10 September 2026, Annexon (ANNX) used the 12th Annual Cantor Fitzgerald Global Healthcare Conference to press its case as a complement-focused drug developer...
In the phase 2 ARCHER study, vonaprument (Annexon Biosciences), formerly known as ANX007, decreased the number of patients with notable vision loss by approximately two-thirds...
The experimental drug could become the first approved treatment for Guillain-Barré syndrome, a paralyzing nerve disease.
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