Annexon reports strong Phase 3 data for tanruprubart in GBS
The therapy met the primary endpoint with significant benefits over placebo and IVIg. MAA is filed in Europe.
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Developer of C1q inhibitors for complement-driven diseases
annexonbio.comLast updated
In short: Annexon reported positive GBS data, filed an EMA application and advanced GA trials.
The therapy met the primary endpoint with significant benefits over placebo and IVIg. MAA is filed in Europe.
First patient outcomes for tanruprubart in GBS show improved muscle strength and disability with no new safety findings at WMS Meeting.
Treatment reduced ICU days and ventilation time while improving independence and recovery rates compared to placebo.
Vonaprument demonstrated significant vision preservation and structural protection compared to sham. Phase 3 ARCHER II trials are underway with results expected in late 2026.
On Thursday, 10 September 2026, Annexon (ANNX) used the 12th Annual Cantor Fitzgerald Global Healthcare Conference to press its case as a complement-focused drug developer...
In the phase 2 ARCHER study, vonaprument (Annexon Biosciences), formerly known as ANX007, decreased the number of patients with notable vision loss by approximately two-thirds...
The experimental drug could become the first approved treatment for Guillain-Barré syndrome, a paralyzing nerve disease.
Rapid, Positive Clinical Outcomes in GBS FORWARD Study Reinforce Consistency and Reproducibility of Tanruprubart Treatment Effect Demonstrated in Phase 3 and Real-World Evidence Studies; BLA...
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