Harness Therapeutics awarded grant from Michael J. Fox Foundation
The grant funds a two-year proof-of-concept study targeting GCase and LIMP2 upregulation via MISBA platform.
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Biotechnology company developing neurodegeneration therapies
harnesstx.comLast updated
In short: Harness Therapeutics advanced its neurodegenerative pipeline by securing MJFF funding and nominating HRN001 as a lead candidate for Huntington’s.
The grant funds a two-year proof-of-concept study targeting GCase and LIMP2 upregulation via MISBA platform.
HRN001 is a first-in-class antisense oligonucleotide upregulating FAN1. The company forms a Clinical Advisory Board to guide clinical progression in 2027.
She brings over 20 years of biopharma experience, including fundraising, partnerships, and leadership roles at Samsara Therapeutics and others. Her expertise supports growth in neurodegenerative therapeutics.
The platform enables simultaneous upregulation and downregulation of two targets. It collaborates with Ono Venture Investment on an R&D program for a rare triplet repeat disorder.
HRN001 is a potent and specific antisense oligonucleotide designed to drive controlled upregulation of FAN1, a genetically validated...
Harness Therapeutics Announces Launch of MISBA® Duo Platform and Research Collaboration with Ono Venture Investment Proprietary MISBA Duo technology is...
(MENAFN- GlobeNewsWire - Nasdaq) Dr Paulo Fontoura brings 20 years' experience of working in the pharma industry, with the most recent 16 years focusing on...
Proceeds to be used to advance lead programme targeting FAN1 nuclease in Huntington's Disease towards the clinic Harness Therapeutics was originally established as Transine Therapeutics...
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