Iovance reports record second quarter 2026 revenue of ~$99M
Total revenue increased 66% year-over-year, gross margin reached 56%, and FDA granted Fast Track for lifileucel in soft tissue sarcomas.
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Biopharmaceutical company developing and commercializing cancer immunotherapies
iovance.comLast updated
In short: Iovance achieved record $99M Q2 2026 revenue, secured international Amtagvi approvals, and advanced its TIL therapy pipeline.
Total revenue increased 66% year-over-year, gross margin reached 56%, and FDA granted Fast Track for lifileucel in soft tissue sarcomas.
The next-generation IL-12 tethered TIL therapy will be evaluated in a Phase 1/2 basket trial for advanced solid tumors, with enrollment starting in H2 2026.
The Therapeutic Goods Administration approved the tumor-derived autologous T cell immunotherapy for previously treated advanced melanoma, marking Iovance's third marketing authorization.
The company guides Q2 2026 revenue to $86-88M and full-year to $350-370M, with a 40% confirmed response rate in endometrial cancer.
The T-cell therapy’s inpatient toxicity is well-characterized, but the risks patients may face after hospital discharge have been unclear.
Biotech stocks advanced on strong quarterly results and pipeline updates. DERM gained on 23% revenue growth and rising Emrosi adoption, while IOVA posted record $99.
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