Taysha announces multiple presentations on TSHA-102 at IRSF meeting
Presentations highlight REVEAL Part A data showing multi-domain functional impact and new insights for pivotal trial design.
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Gene therapy company for CNS monogenic diseases
tayshagtx.comLast updated
In short: Taysha completed dosing in the REVEAL pivotal trial for its Rett syndrome gene therapy and priced a $200 million public offering.
Presentations highlight REVEAL Part A data showing multi-domain functional impact and new insights for pivotal trial design.
The offering includes common stock and pre-funded warrants, with underwriters' option for additional 15%.
Longer-term data show durable functional gains across all patients with Rett syndrome.
The data show scAAV9 yields 30-fold higher MeCP2 expression and miniMeCP2 is functionally comparable to full-length MeCP2.
Taysha Gene Therapies has begun dosing in the phase 3 REVEAL trial for TSHA-102, targeting Rett syndrome with a single intrathecal dose.
Taysha Gene Therapies Inc NASDAQ:TSHA...
Completed dosing of 17 patients in REVEAL pivotal trial; topline data from 6‑month interim analysis and FDA feedback on next steps toward BLA submission pathway...
Jefferies, Goldman Sachs & Co. LLC, Piper Sandler and Cantor are acting as joint book-running managers for the proposed offering. Baird is acting as lead...
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