AL-S Pharma reports positive Phase 2 AP-101 results for ALS
Study met safety endpoints with prolonged survival, delayed ventilatory support, and functional stabilization. Plans advance for confirmatory Phase 3 study.
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Biopharmaceutical company developing antibody therapeutics
neurimmune.comLast updated
In short: Neurimmune expanded its pipeline through a major AstraZeneca deal, secured $150 million in growth funding, and reported positive ALS drug data.
Study met safety endpoints with prolonged survival, delayed ventilatory support, and functional stabilization. Plans advance for confirmatory Phase 3 study.
Exclusive global license agreement targets lambda light chain fibrils in AL amyloidosis. Neurimmune receives upfront payment, up to $780 million milestones, and royalties.
The single-arm, multicenter NI006-102 study evaluates pharmacodynamics and safety of re-treatment in ATTR-CM patients. It assesses changes in cardiac amyloid load, structure, and function.
Renowned ALS neurologist from McGill University will lead AP-101 late-stage development. She served as global principal investigator since 2016.
AstraZeneca has clearly made the rare disease transthyretin amyloidosis (ATTR) a key component of its rare disease pipeline, licensing a second drug candidate in the...
/PRNewswire/ -- Neurimmune today announced that it has expanded on its transthyretin amyloid cardiomyopathy (ATTR-CM) collaboration with Alexion, AstraZeneca...
Neurimmune focusing on the development of immunotherapeutics for the treatment and prevention of human disorders with high unmet medical needs, announced today that it has...
AL-S Pharma today announced positive topline results from the Phase 2 clinical study evaluating AP-101, a potential first-in-class, disease-modifying treatment for amyotrophic lateral sclerosis (ALS...
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