Life Biosciences reports positive Phase 1 ER-100 data for glaucoma
The trial showed ER-100 was well-tolerated with no serious adverse events. Visual improvements occurred in two participants, prompting DSMB approval to escalate the dose.
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Biotechnology company developing cellular rejuvenation therapies
lifebiosciences.comLast updated
In short: Life Biosciences reported positive Phase 1 ER-100 data and raised $80 million in Series D financing.
The trial showed ER-100 was well-tolerated with no serious adverse events. Visual improvements occurred in two participants, prompting DSMB approval to escalate the dose.
The trial evaluates ER-100 for optic neuropathies including glaucoma and NAION, targeting root cause of age-related vision loss.
Funding supports Phase 1 trial of ER-100 for optic neuropathies and advances Partial Epigenetic Reprogramming platform. Announced April 8, 2026.
The clearance enables a Phase 1 trial for ER-100, a cellular rejuvenation therapy, in optic neuropathies like glaucoma and NAION.
Life Biosciences (“Life Bio”), a biotechnology company pioneering cellular rejuvenation medicines to reverse diseases of ...
The experimental treatment by Life Biosciences will deliver three distinct genetic edits to regenerate neurons in the optic nerve, which can be damaged in people...
A Boston company treated its first patient with a therapy intended to allow aging optic nerve cells to behave as though they were young again...
The FDA recently approved the cellular rejuvenation therapy ER-100 for human clinical trials. While vision is the first target, it could have applications for a variety of age-related disease.
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